On the replicability of physiological responses

Abstract

Science is often claimed to be amid a reproducibility crisis, as evidenced by low replicability of many classic findings across multiple fields. Yet it is not clear how widespread this purported problem is. Physiological responses have the potential for replicability issues because of laboratory-specific biases in animal maintenance as well as technically complex methodologies that are often undertaken using bespoke combinations of equipment. Here, we took advantage of a cross-laboratory manipulative study on metabolic rate to assess the replicability of food restriction effects on metabolic scaling and level. Across seven skink species from the Egernia species complex and two universities, ..